1, 5-Anhydroglucitol as Marker of Short-Term Hyperglycemic Excursions in Well-Controlled Type 2 Diabetes Mellitus: Associations with the Prevalence of Vascular Complications
Journal: Diabetes Research And Treatment : Open Access (Vol.2, No. 1)Publication Date: 2015-01-22
Authors : Felix Kulozik; Christoph Hasslacher;
Page : 1-9
Keywords : Type 2 Diabetes Mellitus; Metabolic Control; Intermittent Hyperglycemia; Hemoglobin A1C; 1; 5- Anhydroglucitol; Vascular Complications; Insulin Analogues;
Abstract
The importance of an appropriate and stable long-term mean glycemic control, commonly measured by the HbA1c, for the incidence of diabetic complications has been widely recognized [1β4]. The HbA1c reflects the glycemic metabolism of the past 2-3 months and can therefore be recognized as longterm glycemic marker. In contrast, it is only slightly influenced by short-term glycemic excursions, e.g. states of postprandial hyperglycemia. However, short-term excursions also seem to exhibit pathogenetic significance for the development of vascular complications [5β8].
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