Protein kinase Inhibitors for the Treatment of Inflammatory and Autoimmune Diseases

Protein kinases form an integral part of the enzyme machinery of all cells and play an important role in a large number of cell functions and processes from cell signaling, metabolism and DNA damage response to cell adhesion and proliferation, these enzymes regulate numerous key molecules and constitute one of the largest and most diverse families of enzymes known. While the importance of these molecules has been known for a while now, their potential as therapeutic targets has only recently begun to be explored.