Age-Related Reduction in Blood Flow Velocity in the Middle Cerebral Arteries and the Musculoskeletal System

Work done for the purpose of analysis of the dependence of the pace of age-related decline in speed of cerebral blood flow and functional status of the musculoskeletal system of different groups of patients. Technique: Investigated the blood flow velocity (FV) in middle cerebral arteries (MCA) during the function of muscle samples of healthy people, as well as for injuries and diseases of the extremities (105 people), as well as congenital diseases with impaired growth of the extremities (71) in the treatment by Ilizarov. Results: Based on constructing the equations of linear regression evaluation of age-related decline in the values of FV up to 60% of the constant component revealed that the source healthy people, the prognosis of life expectancy close to the regional norma (69-73 years). At the same time, age-related decline of FV in the MCA is a necessary condition for the preservation of cerebral autoregulation. The case of congenital pathology of the original FV in the MCA below, and the decrease rate is higher. The output of scope change FV in functional tests within the normal range (25%) is accompanied by decreased capacity of patients and slowing down the process of reparative regeneration.