Dynamics of Ischemia-Dependence as Neurodegeneration

Proportional dimensions of molecular misfolding and unfolding afford a profile understanding of a basic neuronal degeneration that is also reflected in the endoplasmic reticulum (ER) response to aberrant degradation of various molecular profiles. The distributional attributes for further progression of proportional attributes arise in terms of a protein aggregation phenomenon that assigns the neurofibrillary dimensions of injury to an ischemic network of neurons in a manner that accounts for specific manifestations of neuronal apoptosis. Incremental profiles for further recharacterization of performance dynamics are well-indexed by systems biology of transfer between endoplasmic reticulum and the Golgi apparatus. In realized evolutionary course for such neurodegeneration, the attributes for further progression to accelerated course further promote permissive dimensions as well-characterized by a failure of homeostatic control for further change in molecular transfer and distribution.