APPLICATIONS AND TECHNIQUES OF TRANSGENIC ANIMALS IN DISEASE DIAGNOSIS AND THERAPEUTIC TARGETS

Transgenic animals are those whose genetic material has been altered and carry the genes of other organisms. This technology is one the latest trends used in the field of biotechnology. It is used to integrate the transgene into the organism and produce the desired trait in an industrial scale.Each has its own advantages and disadvantages and needs further studybecause of unresolved technical and safety issues. They serve as models to study human diseases and its diagnosis and have shown to increases resistance,productivity, hardiness, and feed efficiency and in use of precliniacal studies. In this review the strategies used for drug discovery, preclinical trials using transgenic animals has been discussed and the production of recombinant milk.