THERMODYNAMIC INTERACTION STUDIES OF GYCINE ,D(+)ALANINE AND D(+)VALINE IN AQUEOUS METFORMIN HYDROCHLORIDE AT CONSTANT TEMPERATURE

Density and viscosity ofglycine D(+) alanine and D (+) valine in 0.05 and 0.15 in aqueousmetformin hydrochloride solutions have been determined experimentallyat 308.15 K.The results obtained from density and viscosity measurement have been used to calculate the Hydration number Hn, apparent molar volume фv, , partial molal volume ф0 v , at infinite dilution, transfer volume ∆ф0 tr , free energy of activation per mole of soluteΔ µ2 0#and solvent Δ µ1 0#and B- coefficient. It has been observed that there exist strong solute-solvent interaction and complex formation between in these ternary systems.They have strong structure making ability