DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR ESTIMATION OF SATRANIDAZOLE FROM ITS FORMULATION
Journal: Indian Drugs (Vol.55, No. 10)Publication Date: 2018-10-29
Authors : Shirode A. R.; Dhumal A. P.; Kadam V. J.;
Page : 40-48
Keywords : * For Correspondence: E-mail - arsprojects2014@gmail.com;
Abstract
A sensitive stability-indicating high performance liquid chromatography (HPLC) method was developed and validated for quantitative estimation of satranidazole (SAT), a new nitroimidazole with potent antiamoebic activity and accessible in market as tablet and dry syrup either alone or in combination with ofloxacin. The present study involves the development of simple, accurate, precise, reproducible reversed phase high performance liquid chromatography (RP-HPLC) method for determination of satranidazole from its formulation. Isocratic elution at a flow rate of 1.0 mL/min was employed on Hemochrom Intsil C-18 (250 mm× 4.6 mm, 5
Other Latest Articles
- ESTIMATION OF METFORMIN HYDROCHLORIDE AND TENELIGLIPTIN IN PHARMACEUTICAL FORMULATION BY HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY
- USE OF FACTORIAL DESIGN IN OPTIMIZATION OF MICROWAVE ASSISTED ORGANIC SYNTHESIS OF SOME AZOLES
- SYNTHESIS AND ANTI-DIABETIC ACTIVITY OF SOME ARYLOXYPROPANOLAMINE DERIVATIVES
- A SCIENTIFIC REVIEW ON PHYTO-PHARMACOLOGICAL PROPERTIES OF TRIBULUS TERRESTRIS LINN
- INDIAN PHARMA INDUSTRY – WHAT’S NEXT?
Last modified: 2018-11-01 16:25:19