EFFECT OF ZINC-COPPER HYDROCHLORIDE MIXED CRYSTALS APPLICATION IN RABBITS WITH ACUTE EXPERIMENTALLY INDUCED FASCIOLOSIS

Effects of zinc (Zn) – copper (Cu) hydroxochloride mixed crystals were tested on body weights, body weight gain, mortality, liver vitamins A, C, E, trace elements Zn and Cu and enzyme Cu-Zn superoxide dismutase. Investigated parameters were not changed significantly compared to controls in Zn-Cu hydroxochloride mixed crystals supplemented rabbits. Body weights and body weight gain were reduced, mortality was increased and liver biochemical parameters were decreased in F. hepatica infected animals. All affected parameters were increased near to controls after Zn-Cu hydroxochloride mixed crystals application in infected rabbits, so they may be used for restoration of disturbances from fasciolosis.