Ratios of Magnesium/Trace Element Contents in Prostate Gland as Carcinoma’s Markers

The aim of the study was to evaluate whether significant changes in the prostatic tissue levels of ratios Mg/trace element contents exist in the malignantly transformed prostate. Contents of Mg and 43 trace elements in normal (N), benign hypertrophic (BPH) and cancerous human prostate (PCa) were investigated. Intact prostates of N group were removed at necropsy from 37 men aged 41-87 who had died suddenly. The patients of BPH and PCa groups were hospitalized in the Urological Department of the Medical Radiological Research Centre (Obninsk, Russia). The age of 32 patients with BPH ranged from 56 to 78 years. The 60 patients aged 40-79 suffered from PCa (stage T1-T4).