A 5 years study of parotid gland tumors in a tertiary hospital
Journal: International Archives of Integrated Medicine (IAIM) (Vol.5, No. 11)Publication Date: 2018-11-17
Authors : B. Vijayanirmala T. Sundari Devi Shahistha P.V. Ramana;
Page : 8-13
Keywords : Salivary glands; Parotid neoplasms; Histopathology; Immunohistochemistry; Pleomorphic adenoma; Mucoepidermoid carcinoma.;
Abstract
Background: The salivary glands, mainly parotids are the site of origin of a wide variety of neoplasms. At the same time, they are relatively uncommon and show racial and geographical variations. Majority (80%) are benign tumors, only about 20% are malignant. Histopathology of parotid neoplasms is most complex and diverse of any organ in the body. Also histopathology plays a major role in the diagnosis of these neoplasms with very few contribution using special stains, immunohistochemistry and cytogenetic studies. Aim: The aim of the present study was to analyze the relative incidence, clinical presentation and spectrum of neoplasms in the parotid glands with their micromorphology at Gandhi hospital, Secunderabad, which is a tertiary referral hospital in Telangana state. Material and methods: A retrospective and prospective study of all parotid gland tumors received in the department of pathology for histopathological examination at Gandhi hospital, Secunderabad during a period of 5 years, from January 2013 to January 2018 was done. The clinical data like age, sex, duration were recorded. Grossly representative bits from the tumors were processed, sections made, stained with routine Hematoxylin and Eosin and examined under microscope. Data of 48 cases recorded during the 5 years period was analyzed. Results: 48 cases were studied during the 5-year period. Of them 39 cases were benign neoplasms and 8 cases were malignant. Benign tumors were more common in the parotid gland compared to malignant tumors, the most common benign tumor being Pleomorphic adenoma. Mucoepidermoid carcinoma was the most common malignant tumor. Most of the benign tumors occurred in the 3rd and 4th decade while the malignant tumors were more common in the 6th decade. Conclusion: Pleomorphic adenoma is the most common benign tumor and Mucoepidermoid carcinoma is the most common malignant tumor.
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