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TITLE Solitary fibrous tumour of pleura with malignant form and prolonged aPTT presenting as massive pleural effusion

Journal: University Journal of Medicine and Medical Specialities (Vol.4, No. 5)

Publication Date:

Authors : ;

Page : 85-86

Keywords : Key wordsSolitary fibrous tumour of pleura; Benign; Malignant;

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Abstract

Abstract Solitary fibrous tumour of pleura Other names-Localised mesothelioma, Benign fibrous mesothelioma,Benign localised fibroma.This tumour uncommon,involves age group around 5th decade usually,biologically,histologically benign appear as firm encapsulated tumour arising from visceral pleura in 70 cases and from parietal pleura in 30casescomposed of elongated spindle cells,collagen and reticulin fibres. This tumour lacks cytoplasmic, keratin expression but expresses CD34 and v i m e n t i n . M a n i f e s t i n t w o f o r m s m o r p h o l o g i c a l l y - 1 . p e d u n c u l a t e d t y p e - g o o d prognosis,2.sessile typemostly malignant-worst prognosis. Mostly asymptomatic but may present with chest pain, dyspnea,and cough.Transthoracic needle biopsy is the diagnosis of choice.RadiologicallySolitary, sharply defined discrete mass located at the periphery of lungfield associated with pleural effusion in 20 cases.Surgery is the major mode of treatement.

Last modified: 2018-12-07 16:45:30