Comparison of comorbidities between rheumatoid and psoriatic arthritis in a tertiary care rheumatic center

Introduction: Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) have key differences in clinical presentation, radiographic findings, comorbidities and pathogenesis to distinguish between these common forms of chronic inflammatory arthritis. Joint involvement is typically, but not always, asymmetric in PsA, while it is predominantly symmetric in RA. Bone erosions, without new bone growth, and cervical spine involvement are distinctive of RA, while axial spine involvement, psoriasis, and nail dystrophy are distinctive of PsA. Aim of the study: To Compares the comorbidities between Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PSA). Materials and methods: This was a prospective observational study conducted for a period of 6 months at Institute of Rheumatology, Government K.A.P.V. Medical College and MGM Government Hospital. Totally 241 patients who were fulfilling inclusion criteria has been included. Patients diagnosed with and treated for PsA on the basis of clinical, radiological and laboratory findings and expert opinion was monitored using standardized examination methods and jointly prepared forms. Clinical status, accompanying systemic diseases and surgical history was recorded. Routine clinical examination and basic comorbid findings have been assessed by standardized methods. Results: Two hundred and forty-one patients were included in the study. 179 patients were diagnosed with RA (male -15, female -164) and 62 were diagnosed with PsA (male - 44, female -18). Comorbid systems such as diabetes, hypertension, metabolic syndrome, cardiovascular disease, transaminitis, malignancy, hyperuricemia were more in RA group when compares to PsA. Which shows statistically significant of p-value <0.005. Conclusion: Though both Rheumatoid arthritis and Psoriatic arthritis are associated with enhanced cardiovascular morbidity, markers of morbidity are more in the RA group when compared to PsA except that patients with psoriatic arthritis have more hyperuricemia and transaminitis.