Topical Phytotherapy: Management of Deranged Anatomical and Abnormal Biochemical Risk Factors during Failed Total Knee Arthroplasty: A Unique Case Study

Total knee arthroplasty (TKA) is the ultimate answer to treat knee osteoarthritis (KOA) worldwide. The main purpose of TKA is to relief pain and to improve the day to day functional activities. But during failed TKA, various abnormal anatomical features and other biochemical risk factors develop in the serum of the patients along with pain and disability of performing daily activities persist. The present case study was aimed to normalize the deranged anatomical features and elevated levels of biochemical parameters, to relief pain syndromes and to improve daily physical functional abilities without revision of failed TKA correlated with radiological images with the help of topical phytotherapeutic treatment protocol. Five Indian patients were advice to undergo revision of TKA. They refused to do the further surgery and treated in OPTM Health Care (P) Ltd for 13 weeks. Anatomical measurements included the gap at the knee between the short head of the biceps femoris and the level of the bed, diameter of muscles at the thigh, the calf and, straight leg raising and knee flexions and extensions in different postural positions for both the legs, and biochemical parameters such as serum C-reactive protein (CRP), creatine kinase-muscle (CK-MM) and aldolase A (Aldo A) were measured pre- and post-treatment of 13 weeks using appropriate instruments. The results indicate the percentage of improvements for all abnormal anatomical and biochemical features were highly statistically significant (p<0.0001), pain under VAS (p<0.0001), pain, stiffness and physical functions under WOMAC Index all are highly significant (p<0.0001) and parameters under KOOS (p<0.0001) and BMI (p<0.0001) with improved radiological images after 13-week of post-treatment. In conclusion, the deranged anatomical and elevated levels of biochemical risk factors, impaired acute pain syndromes, and day to day functional activities including quality of life with abnormal increased body weight developed during failed total knee arthroplasty can be normalized with the help of topical phytotherapeutic treatment protocol within 13 weeks.