Metabolic Effects of D-Chiro-Inositol and Myo-Inositol in Polycystic Ovary SyndromeJournal: International Journal of Clinical Endocrinology and Metabolism (Vol.3, No. 1)
Publication Date: 2017-12-07
Authors : Rim Hanna Tarek Wehbe; Elizabeth Abou Jaoude;
Page : 029-033
Keywords : Inositols; Polycystic ovary syndrome; Insulin resistance; Metabolic pro fi le;
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. The pathogenesis has not been fully deciphered. PCOS is associated with insulin resistance (IR), menstrual irregularities, cardiovascular disease, obesity, hirsutism, infertility, and endometrial cancer. The use of D-chiro-inositol (DCI) for the treatment of IR in PCOS has been controversial with contradictory data being published. Our objective is to evaluate the effect of DCI combined with myo-inositol (MI), and metformin on the metabolic outcomes of PCOS in a Lebanese women cohort.
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