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THE HEPATOTOXICITY OF MIMOSINE IN PRECISION CUT GOAT LIVER SLICE SYSTEM

Journal: Exploratory Animal and Medical Research (Vol.1, No. 1)

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Authors : ; ; ; ; ;

Page : 29-33

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Abstract

Mimosine, a non protein toxic amino acid, induced toxicity in precision cut goat liver slice system had been studied in term of its effect on certain enzymatic and metabolic parameters in vitro. Significant depletion of tissue sulfhydryl groups (TSH, PBSH and NPSH), rise in lipid peroxidation and altered membrane bound ATPases activity were observed during the study suggestive of hepatotoxic effects of mimosine.

Last modified: 2014-07-20 18:16:49