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A new flavonoid glycoside from Trichilia emetica

Journal: Journal of Medicinal and Chemical Sciences (Vol.2, No. 4)

Publication Date:

Authors : ; ; ;

Page : 144-150

Keywords : Trichilia emetica; Catechin; Nuclear magnetic resonance; Bioassay;

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Abstract

A new compound, catechin-3-O-α-L-rhamnopyranosyl (1→4) β-D-glucopyranoside was isolated from the ethylacetate soluble fraction of the aqueous extract of the whole seeds of Trichilia emetica (Family: Meliaceae). The structure of this compound was established on the basis of nuclear magnetic resonance (NMR), Infrared (IR) spectroscopy and ultraviolet-visible (UV-vis) spectrophotometry. The compound was also subjected to antimicrobial activity and brine shrimp lethality bioassay. The pure compound showed either no or reduced activity against microorganisms tested, it also showed no cytotoxicity.

Last modified: 2019-03-24 21:46:51