A new flavonoid glycoside from Trichilia emetica
Journal: Journal of Medicinal and Chemical Sciences (Vol.2, No. 4)Publication Date: 2019-07-01
Authors : Abdullahi Usman; Vera Thoss; Mohammad Nur-e-Alam;
Page : 144-150
Keywords : Trichilia emetica; Catechin; Nuclear magnetic resonance; Bioassay;
Abstract
A new compound, catechin-3-O-α-L-rhamnopyranosyl (1→4) β-D-glucopyranoside was isolated from the ethylacetate soluble fraction of the aqueous extract of the whole seeds of Trichilia emetica (Family: Meliaceae). The structure of this compound was established on the basis of nuclear magnetic resonance (NMR), Infrared (IR) spectroscopy and ultraviolet-visible (UV-vis) spectrophotometry. The compound was also subjected to antimicrobial activity and brine shrimp lethality bioassay. The pure compound showed either no or reduced activity against microorganisms tested, it also showed no cytotoxicity.
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Last modified: 2019-03-24 21:46:51