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A clean and efficient synthesis of spiro[4H-pyran-oxindole] derivatives catalyzed by egg shell
Journal: Iranian Chemical Communication (Vol.7, No. 2)Publication Date: 2019-03-01
Authors : leila Youseftabar-Miri;
Page : 142-152
Keywords : Spirooxindole; eggshell; heterogeneous catalyst; isatin; green chemistry;
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Abstract
Egg shell has been utilized as a natural, green, reusable and eco-friendly reagent for the synthesis of spiro[4H-pyran-oxindole] derivatives by one-pot multicomponent reaction of isatins, 1,3-diketones, and malononitrile/ ethyl cyanoacetate. Good functional group tolerance and broad scope of usable substrates are other prominent features of the present methodology.
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Last modified: 2019-06-26 14:29:13