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Study of Immunogenicity and Protective Efficacy of Live MDCK-derived Pandemic Influenza Vaccine
Journal: Global Journal of Infectious Diseases and Clinical Research (Vol.5, No. 1)Publication Date: 2019-03-19
Authors : Elena A Nechaeva Ryzhikov AB Pyankova OG Radaeva IF Pyankov OV Danilchenko NV Agafonov AP Kiseleva LV Larionova NV; Rudenko LG;
Page : 010-015
Keywords : A/H1N1 (2009) Pandemic infl uenza; Aerosol challenge; Ferrets; Live vaccine; MDCK cells; Virus;
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Abstract
Background: The threat of pandemic A/H1N1 influenza is still a matter of considerable public concern. Influenza outbreak in 2009 underlined the importance of rapid production of a sufficient vaccine reserve for pandemic and interpandemic periods. One promising way to allay this concern is development of cell culture-derived live attenuated influenza vaccines (LAIV), because this technology makes it possible to produce a considerable amount of vaccine over a short period of time.
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Last modified: 2019-06-27 21:44:14