Addiction and Evolutionary Process, Common Aspects in Physio-Pathologic Pathways Useful in Pharmaco-Toxicological Approach

Observing vertebrates evolutionary in mammalian are present characteristic pathways involved in progeny take care in first period after birth. In this behavior and instinct, learning neuronal circuits are evolved and reward mechanism the same. In addiction is possible to observe that definite neuronal circuits play a crucial role. In this work are showed this similarity to better understand the addiction condition. Reward mechanism (primary, intrinsic or extrinsic) is involved in food, reproductive- sexual activity but also in other human condition. Conditioning, reinforce, reward, learning behavior, depression status, level of motivations are common concept involved also in addiction.