Antibiotic Sensitivity of Fungi Isolated from Patients with Sinusitis

Objectives: The present study aimed at identifying the fungi that accompany sinusitis patients and the possibility of controlling them using antifungal agents. Methods: Seventy eight swabs were taken from patients with sinusitis to the Diwaniyah Teaching Hospital for the period from November 2012 to April 2013 for the purpose of isolating and diagnosing the fungi associated with sinusitis and testing their susceptibility to the antifungal agents In a disc method and minimum inhibitory concentration. Results: The fungus Aspergillus sp was the first fungus in terms of the number of isolates and the percentage of its frequency in sinus patients, as the isolates was 14 isolates, representing 31.8%, penicillium spp in the second ,the percentage was 18.18% from 8 isolates of the total number of fungi, the fungus Cladosporium sp and B.dermatitidis came third in terms of the number of isolates and the percentage of the emergence where they appeared 11.36% form five isolates of the total isolates, while Ttichophyton sp and Alternaria sp came fourth and were followed by Ulocladium sp, Rhizopus sp, Mucor sp, Trouulpsis sp, Bipolaris sp, Rhodotorula sp, Pacilomyces sp and Geotrichum sp. Antibiotic sensitivity test by disc method showed a significant difference in inhibiting of growth of Penicillium sp by the antifungal ketoconazole with an inhibitory capacity of 36 mm. The antifngal Econazole 30 mm and nystatin 28 mm. Aspergillus sp, Econazole and Nystatin were the most effective in inhibiting of its growth. The same applies to the rest of the isolated fungi. Econazole and Nystatin are superior to the rest of the antifungal agents. Conclusion: The sinuses are a suitable place for the growth of many opportunistic fungus for nutrients, heat and darkness suitable for the growth of these fungus, especially Aspergillus sp and penicillium sp. Ketoconazole is effective in inhibiting the growth of these fungi and clotrimazole is second grade.