TO STUDY THE EFFECT OF KANTAKARYAVALEHYA ON EOSINOPHIL CATIONIC PROTEIN (ECP) LEVELS IN CHILDHOOD ASTHMA

Background:Childhood asthma is one among the most common causes for hospital visits in India. It has its impact on the socio-economic and psychological factors of the sufferers. School absenteeism in children due to childhood asthma is not uncommon. Ayurveda line of treatment can be of immense help in preventing and providing succor to patients. This study was intended to assess the efficacy of Kantakaryavalehya clinically and on ECP levels in Childhood asthma. Objectives: This research study had two objectives 1. To assess the efficacy of Kantakaryavalehya on Childhood asthma clinically 2. To assess the efficacy of Kantakaryavalehya on Eosinophil Cationic Protein levels in Childhood asthma. Methods: 20 childhood asthmatics were selected for the study. They were administered with the trial drug Kantakaryavalehya for 90 days with assessment at interval of every 30 days. Blood was drawn before and after the study period to evaluate the serum ECP levels. GINA guidelines 2016 was followed for clinical assessment of Asthma. Results:In both clinical and objective evaluations, results were encouraging. Clinical assessment of level of asthma control was found statistically marginally significant (p-0.059), improvement in terms of PEF rate was highly significant (p=0.03). Assessment of ECP levels in serum and comparison before and after treatment showed marginally statistically significant results (p-0.07). Though the effect of Kantakaryavalehya on ECP levels was marginally significant, it was strikingly evident in terms of clinical improvement and with respect to PEFR. Conclusion:Kantakaryavalehya may be used as a drug of choice in the management of Childhood asthma.