EVALUATION OF HEALTH RELATED QUALITY OF LIFE AMONG ISCHAEMIC STROKE PATIENT IN INDONESIA USING EQ-5D-5L

The aims of this study were to show the health-related quality of life of ischemic stroke patient and to observe the effect of disability and stroke complications on EQ5D-5L utility index. this was a cross-sectional study conducting on ischemic stroke patient in 10 hospitals located in Special Region of Yogyakarta, Indonesia. The subjects of this study were collected with the inclusion criteria as follow; age > 18 years, having a stroke for the first time, and taking rehabilitation treatment in the hospital after being discharged from inpatient ward.Health-related quality of life was measured using EQ-5D-5L during outpatient rehabilitation treatment after stroke. Disability was described using modified Rankin Scale (mRS) while stroke complications were categorized usingCharlson Index Score. A value set established for Indonesian population was used to represent utility estimates. The findings on 350 stroke ischemic patients, consisted of 87.14% patients aged > 50 years and 57.43% male, showed the average utility score and visual analogue scale (VAS) were 0.376±0,511 and 74,24±15.27, respectively. Eighty percent patients reported difficulty on walking, 64.86% on self-care, 71.71% on usual activities, 76.29% on pain/discomfort, and 70.86% on anxiety/depression. There were significant different on utility score regarding the age, level of education, employment status, level of disability and comorbidity. The higher the disability levels, the lower the health utility index. Patients with severe disability (mRS = 5) had utility score of -0.563 (95% CI, - 0.651 – -0.476), otherwise, patients without disability and symptoms (mRS = 0) had utility score of 0.927 (95% CI, 0.876 – 0.978). Comorbidity and level of disability of ischemic stroke patients were associated with health-related quality of life. The higher the disability levels, the lower the health utility index.