The functional state of the system of immunological protection in traumatic disease in patients with an increased body mass index

The purpose of this study was to analyze the functional state of the system of immunological protection in traumatic disease in patients with an increased body mass index (IВMІ). Using systemic multivariate analysis, the integral indicators of immunogenesis were determined on the basis of a dynamic study of 1344 complex immunograms in 224 patients with IВMІ with polytrauma and different starting figures оf BMI. The patients were divided into 3 groups: group I included patients with a BMI to 29.9; group II – patients with a BMI 30.0 –39.9; group III – patients with a BMI > 40.0. The study was conducted on the 1, 3, 7, 14, 30 and 360 days from the moment of receiving polytrauma. Our analysis allowed us to prove objectively on mathematical models that traumatic disease is a long process. Clinical and pathogenetic aspects of immune disorders do not cause doubts and provide grounds for the application of the proposed treatment algorithms and changes in stereotypes regarding the approach to treatment in general.