Post transplant bone disease

Mineral and bone diseases (MBD) are common in patients with chronic kidney disease who undergo kidney transplantation. After successful reversal of uremia by kidney transplantation, many bone and mineral disorders improve, while immunosuppression, other medications, and new and existing co morbidities may result in new or worsening MBD.We report a renal transplant recipient who presented with severe bone pain, accompanied with difficulty in walking. Evaluation revealed severe lytic bone lesions and hyperparathyroidism. She was treated with calcium and vitamin D supplements, along with cinacalcet, following which there was dramatic improvement in bone pain and proximal weakness.