Histopathological evaluation of endometrium in Postmenopausal bleeding

Aims & Objectives: 1. To evaluate various causes of postmenopausal bleeding in terms of functional and organic endometrial lesions on histopathological basis, 2. To confirm or to rule out the diagnosis of atypical or malignant endometrial lesions. 3. To help the gynecologists in diagnosis of endometrial cancer as early as possible. Materials and Methods: The study was carried out in the Department of Pathology, GMERS Medical College-Junagadh from January 2015 to September 2018 and includes 200 cases of postmenopausal women who presented with bleeding problems at our institute. Histopathological evaluation of endometrium was done in all these cases after clinical evaluation and final diagnosis was given in terms of organic or functional lesions. Results: Out of 200 cases, 36 cases (18%) showed organic lesions & 164 cases (82%) showed functional lesions. Among organic lesions, Simple & Typical Hyperplasia was the commonest one (12 cases), while among functional lesions, Atrophic Endometrium was the commonest one (88 cases). Atypical and Malignant lesions were commonly seen after 60 years of age. Conclusion: The role of histopathology remains always important in the evaluation of postmenopausal bleeding. Careful histopathological evaluation of endometrium is always necessary in order to confirm or to rule out premalignant or malignant lesions in order to save the patient's life.