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Journal: International Journal of Advanced Research (Vol.7, No. 7)

Publication Date:

Authors : ; ;

Page : 864-867

Keywords : MRSA (Methicillin resistant Staphylococcus aureus) ESBL (Extended spectrum beta lactamases) MBL (Metallo-beta- lactamases) Opportunistic infection.;

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Introduction:Most common cause of morbidity and mortality among burn patients is infection. Infection contributes to approximately 75% of mortality among burn patients. These patients are often susceptible to opportunistic infections. The aim of the present study is to study the bacteriological profile and antibiotic susceptibility pattern of these isolates among burn patients. Material &method:Samples were collected from total 120 patients using sterile swab, from which 136 organisms were isolated and identified using standard procedures. Antibiotic susceptibility testing was done as per CLSI guidelines. Result:From a total of 120 burn patient?s swabs were collected. From which 115 (95.83%) were culture positive and 5 (4.16%) were culture negative. A total of 136 bacterial isolates were obtained from the patients. Majority of bacterial isolates were gram negative 123 (90.44%) while gram positive isolates were 13 (9.55%). Females were most commonly affected by burn accounting to 61% of cases as compared to males which were affected in 39% of cases. Most common age group affected in either sexe?s was 21-30 years (71.30%) followed by 31-40 years (19.13%). Burns in most of the cases was due to flame 110 (96%) followed by electrocution 5 (4%). Most common bacteria isolated from burn patients was Pseudomonas aeruginosa 98 (72%) followed by Staphylococcus aureus 13 (9.555%), Klebsiella species 20 (14.70%), Acinetobacter species 3 (2.20%) and Proteus species 2 (1.5%). Among Staphylococcus aureus 13 (9.55%) isolated from burn patients, high rate of MRSA 12 (92%) were seen while MSSA 1 (8%) case was seen. Antibiotic susceptibility pattern among gram negative bacteria showed high sensitivity to Imipenem 114 (94%) followed by Piperacillin tazobactam 112 (71.05%), Amikacin 110 (89.43%), Ceftazadime 104 (84.55%). Least sensitivity was seen for Cotrimoxazole (44%) and ciprofloxacin 49% in gram negative isolates. Among gram negative isolates 12.2% isolates were ESBL producers while 4.4% isolates were MBL producers. Among gram positive isolates 100% sensitivity for seen for vancomycin & Linezolid followed by Amikacin 12 (92.30%), Erythromycin 8 (61.53%),clindamycin 7 (54%). Least sensitivity was seen for Cefoxitin 7.7%. Among gram positive bacteria 92% isolates were MRSA.

Last modified: 2019-09-04 18:52:56