QUANTITATIVE ASSESSMENT OF VASICINE AND VASICINONE IN DIFFERENT MARKETED FORMULATIONS USING HPLC

The main aim was to study the variation in vasicine and vasicinone concentration in different marketed cough syrups using HPLC with photo-diode array detector. Since the marketed formulations were containing Adhathoda vasica extract of varying amount, the amount of vasicine, which is the main constituent, deviated extensively. Also a complete and effective extraction method for quantitative estimation of vasicine and vasicinone from these formulations has been developed. Subsequently, based on the results, it was concluded that the need arises to standardize these marketed formulations. Year 2019 | Volume No. 56 | Issue No.08 | Page No. 79-80