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AGE OF ONSET OF TYPE 2 DIABETES CORRELATES WITH GENETIC VARIABILITY IN THE GENOMIC AREA OF IGF2

Journal: Indian Journal of Medical Research and Pharmaceutical Sciences (Vol.1, No. 1)

Publication Date:

Authors : ; ; ;

Page : 4-8

Keywords : Onset of T2D; IGF2 genomic area; Type 2 Diabetes; Insulin genomic area; Sex; Obesity;

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Abstract

Four polymorphic sites in insulin gene genomic area were analyzed by DNA analysis in 91 subjects with T2D. Two sites included in IGF2 area show a statistically significant association with age of onset of T2D. Such association is highly significant in females (p=0.002) and in obese subjects (p=0.004).

Last modified: 2014-08-21 21:53:35