Chemical Stability of Pharmaceutical Organic Compounds | Biomedgrid

According to the reaction conditions, medicines or pharmaceutical organic compounds can be altered via hydrolysis or elimination reactions. They can also degrade through isomerisation, oxidation or polymerization. This review aims to show the reaction mechanisms related to the stability of medicines. In that context, mechanisms are useful in order to explain the formation of products into the chemical reaction medium. When medicines are in an inadequate reaction medium, they disintegrate accordingly. Therefore, it is very important to understand the conditions which modify the stability of medicines so that to identify means to ensure their stability. Indeed, the chemical or physical degradation can alter the therapeutic efficiency of a medicine and it can lead to the production of undesirable products