Phylogeny of Human Mitochondrial DNA Lineages and Its Applications

With the special intention to introduce the most widely adopted phylogenetic analysis human mitochondrial DNA (mtDNA) studi,the history of the reconstruction of mt DNA phylogny was reviewed. And the applications of human mtDNA phylogeny in studying human evolution, estimating the quality of mtDNA data, and distilling the disease-associated mtDNA mutation were then summarized in the present review.