IN VITRO LIPID PEROXIDATION INHIBITORY AND ANTI-ARTHRITIC ACTIVITIES OF SOME INDIANMEDICINAL PLANTS

Anti-lipid peroxidation effect of aqueous extracts of Ocimum sanctum, Tinospora cordifolia and Withaniasomnifera was evaluated against Fe2+-ascorbic acid-induced lipid peroxidation using rat liver mitochondriaas model system, whereas, anti-arthritic activity was evaluated by proteinase inhibitory assay. O. sanctumshowed potent anti-lipid peroxidation and anti-arthritic activities. T. cordifolia exhibited moderate anti-lipidperoxidation activity, but considerable anti-arthritic activity, whereas, W. somnifera revealed least lipidperoxidation inhibitory activity and considerable anti-arthritic activity. Besides, Folin-Ciocalteu reagentin terms of gallic acid equivalent achieved the total phenolic content and the trend was found to be O.sanctum > T. cordifolia > W. somnifera.