INSULIN SECRETAGOGUE POTENTIAL OF FERONIA ELEPHANTUM FRUIT EXTRACT IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Journal: Indian Drugs (Vol.49, No. 8)Publication Date: 2012-08-28
Authors : Khatib N. A. Patil P. A.; Ismail P.;
Page : 45-50
Keywords : *E-mail: khatibnayeem@hotmail.com;
Abstract
Methanol extract of Feronia elephantum fruit at a dose of 400 mg/kg twice a day, was evaluated for its insulin secretagogue potential in streptozotocin (STZ) 50 mg/kg induced diabetic rats. Treatment showed significant (P<0.001) decrease in blood glucose and significant (P<0.001) increase in seruminsulin, hepatic, muscle glycogen content and restoration of disturbed dyslipidemia. Result obtained from the present study indicates that methanol extract of Feronia elephantum fruit has insulin secretagogue potential in STZ induced diabetic rats.
Other Latest Articles
- SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF SOME NEW 1, 3, 4-OXADIAZOLES
- ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF CEFIXIME AND OFLOXACIN IN TABLETS BY RP-HPLC METHOD
- EVALUATION OF TRAPA BISPINOSA STARCH AS AN ALTERNATIVE TABLET EXCIPIENT TO MAIZE STARCH: ASSESSMENT BY PREFORMULATION AND FORMULATION STUDIES
- ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES IN ENDOPHYTIC FUNGI ISOLATED FROM CELASTRUS PANICULATUS
- SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NOVEL S-SUBSTITUTED PHENACYL-1, 3, 4-TRIAZOLE-THIOL DERIVATIVES FOR ANTIMICROBIAL STUDIES
Last modified: 2020-05-28 14:39:34