NEW LANOSTENE-LINKED DEHYDROABIETIC ACID DERIVATIVES FROM THE OLEO-RESIN OF PINUS ROXBURGHII SARG. (PINACEAE)

Pinus roxburghii Sarg.; syn. Pinus longifolia Roxb. (Pinaceae), found in the Himalayan region, furnishes an oleo-resin which is used as insecticides, disinfectants and to treat boils and gastric troubles. Phytochemical investigation of the oleo-resin gave four new triterpenic acids linked with dehydroabietic acid derivatives characterised as lanost-5,20(21),22,25(27)-tetraen-26-oic acid-3β-olyl (3→19')-3'- oxodehydroabietic acid (roxburghianoic acid A, 2), lanost-5,9(11), 20(21), 22,25(27)-pentaen-26-oic acid 3β-olyl-(3→19')-3'-oxodehydroabietic acid (roxburghianoic acid B, 3), lanost-5,7,20(21),22,25(27)- pentaenyl-26-oic acid (3→19')-3'-oxodehydroabietic acid (roxburghianoic acid C, 4), lanost- 5,7,20,22,25(27)-pentaen-26-oic acid 3β-olyl-(3→19')-3'-oxodehydroabietic 16'-dioic acid (roxburghianoic acid D, 5) along with the known phytoconstituent identified a dehydroabietic acid (1). The structures of all the isolated compounds were elucidated on the basis of spectral data analysis and chemical reactions.