Correction of some indicators of blood of turkeys with cytomedines at different stages of growth and development

The effect of thymogen was determined by the formation of the central organ of the immune system in turkeys - fabric bag and peripheral organ - the spleen. Data on the effect of the drug on the relative weight of the fabric bag of turkey embryos. According to the data obtained, thymogen at a dose of 0.05 μg / egg causes the maximum increase in the relative weight of the fabric bag in turkey embryos. When compared with the control, this indicator was 1.47 times higher (P <0.01). When using thymogen at a dose of 0.1 μg / egg, the weight of the fabric bag increased 1.36-fold (P <0.01) compared to the control. A high dose of thymogen (up to 0.2 μg / egg) adversely affected the relative weight of the fabric bag. This group of embryos showed a decrease in the relative weight of the fabric bag by 1.55 times (P <0.001) compared with embryos, which injected 0.05 µg / egg thymogen into the chorion-allantoic shell and 1.05 times higher compared to the control. With the administration of thymogen embryos at a dose of 0.4 μg / egg the relative weight of the fabric bag decreased compared to the previous embryo group, but remained above control. It was found that the maximum increase in the relative mass of the spleen was observed with the introduction of thymogen at a dose of 0.1 μg / egg. Compared to controls, the relative mass of the spleen increased 1.69 times (P <0.001). An increase in its weight by 1.39 times (P <0.01) when compared with the control was observed with the introduction of thymogen at a dose of 0.05 μg / egg. Increasing the dose of thymogen to 0.2 and 0.4 μg / egg increased the relative mass of the spleen compared to the control by 1.04 and 1.08 times, respectively. However, when compared with the experimental group (0.1 μg of thymogen per egg) there was a 1.63-fold decrease in spleen mass (P <0.001). These data indicate a positive effect of thymogen on metabolic processes in the body. A significant (P <0.05) increase in hemoglobin content from 85.32 ± 1.18 g / l in turkeys in the control group to 97.51 ± 1.40 g / l in turkeys treated with thymogen was found. Serum content of total protein increased from 24.56 ± 0.84 g / l to 29.59 ± 0.73 g / l (P <0.01), total lipid concentration - from 1.52 ± 0.03 g / l to 2.18 ± 0.04 g / l (P <0.001). Thus, these data indicate a positive effect of thymogen on the growth and development of immune competent organs of turkeys and on the subsequent level of immune processes in turkeys. It can reduce the effect of abiotic factors that occur in the technological process and in violation of conditions for growing turkeys.