Dapagliflozin: a new adjunct in the treatment of Type 2 diabetes mellitus
Journal: International Journal of Basic & Clinical Pharmacology (Vol.5, No. 4)Publication Date: 2014-08-01
Authors : Mamta Sachdeva; Sameer Dhingra; Milind Parle;
Page : 741-747
Keywords : Type 2 diabetes mellitus; Sodium-glucose cotransporter 2 inhibitor; Dapagliflozin;
- Dapagliflozin: a new adjunct in the treatment of Type 2 diabetes mellitus
- Nephroprotective effect of dapagliflozin in type 2 diabetes mellitus: A potential role of Klotho protein
- EFFECT OF DAPAGLIFLOZIN ON THE LEVEL OF URIC ACID DURING ASYMPTOMATIC HYPERURICEMIA IN PATIENTS WITH DIABETES MELLITUS TYPE 2 AND CONCOMITANT ARTERIAL HYPERTENSION
- To study the antihyperglycaemic and lipid lowering effect of garlic as an adjunct to metformin in patients of type 2 diabetes mellitus with obesity
- Oxidizing modification of albumens in plasma of blood of patients by diabetes mellitus of type 2 iin dependence on degree of indemnification of carbohydrate exchange and duration of diabetes mellitus of type 2
Abstract
Diabetes mellitus (DM) Type 2 is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. The classic symptoms are excess thirst, frequent urination, and constant hunger. Management of Type 2 diabetes focuses on lifestyle interventions, lowering other cardiovascular risk factors, and maintaining blood glucose levels in the normal range. There are several classes of anti-diabetic medications available and these include sulfonylureas, nonsulfonylurea secretagogues, alpha glucosidase inhibitors, thiazolidinediones, glucagon-like peptide-1 analog, and dipeptidyl peptidase-4 inhibitors. Recently, dapagliflozin (Farxiga™), a sodium-glucose cotransporter 2 inhibitor has been approved by Food and Drug Administration as an adjunct to diet and exercises to improve glycemic control in adults with Type 2 DM.
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Last modified: 2014-10-26 15:29:07