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A STUDY ON EFFECTS OF THROMBOCYTOPENIA IN PREGNANCY AND FETOMATERNALOUTCOME

Journal: International Journal of Advanced Research (Vol.8, No. 8)

Publication Date:

Authors : ; ;

Page : 1282-1293

Keywords : Thrombocytopenia Pregnancy Gestational Thrombocytopenia. Immune Thrombocytopenia Hellp Syndrome Thrombotic Thrombocytopenic Purpura;

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Abstract

Introduction:Thrombocytopenia, defined as blood platelet count below 150,000/μL is the second leading cause of blood disorders in pregnancy after anemia. Pregnant women with thrombocytopenia have a higher risk of bleeding excessively during or after childbirth, especially if they need to have a cesarean section or other surgical intervention during pregnancy, labor or in the puerperium. The main aim of this study was to determine the prevalence of thrombocytopenia among pregnant women attending antenatal care service at Department of Obstetrics &Gynaecology, DeenDayal Upadhyay (DDU) Hospital, Hari Nagar, New Delhi. Materials and Methods:A was used to assess the prevalence of thrombocytopenia among pregnant women attending antenatal care service at DeenDayal Upadhyay (DDU) Hospital, Hari Nagar, New Over 11 months 774 women were screened, out of which 62 patients with platelet count less than 1.5 X 109 /L were included in the study, 44 antenatal women could be followed till 8 weeks postpartum. These 44 patients were included in final analysis. and a structured pre-tested questionnaire was used to obtain sociodemographic information, nutritional factors, obstetrics and gynecological factors, history and clinical condition. Collect Blood samples for platelet count and other platelet parameters,. Descriptive statistics will be analyzed with SPSS version 20.0 software. Continuous variables are presented as mean ± SD. Categorical variables are expressed as frequencies and percentages. The Pearsons chi-square test or Fishers exact test is used in determining the relationship between two categorical variables. P<0.05 is considered statistically significant. Result: Total 774 antenatal women who visited our antennal OPD and were subjected to platelet count during the study period, of which 62 patients with platelet count less than 1.5 X 109 /L were included in the study, 44 antenatal women could be followed till 8 weeks postpartum. These 44 patients were included in final analysis. In present study, the incidence of maternal thrombocytopenia was 8.01% Conclusion: The prevalence of thrombocytopenia was 8.01% predominantly with mild type of thrombocytopenia. An accurate diagnosis and risk assessment in the antenatal period is essential for developing specific plans for any antenatal interventions and for management of delivery and the postpartum periods, and the neonate. In developing countries like India, diseases like Malaria and Dengue which are uncommon in other parts of the world, add to the morbidity of the condition and prove to be challenging and pose a management dilemma. Thrombocytopenia was higher among pregnant women who lived rurally. Therefore, health care providers should screen routinely for thrombocytopenia to avoid excessive bleeding during pregnancy.

Last modified: 2020-09-24 20:39:29