ASSESSMENT OF STRUCTURE OF ACUTE EXOGENOUS POISONINGS IN CHILDREN OF THE RYAZAN REGION FOR 2013-2017

Aim. The study of the structure of acute exogenous intoxications in children and adolescents of the Ryazan region in dynamics in 2013-2017. Materials and Methods. A retrospective analysis of 548 cases of acute intoxications in children of the age from 2 months to 17 years hospitalized to the pediatric department and to the department of pediatric resuscitation and intensive care of City Clinical Hospital №11 of Ryazan in the period from 2013 to 2017 was performed. Results. Most intoxications were observed in young children (35.6%) and adolescents (45.1%). Prevailing etiological factors of acute intoxications in children and adolescents were medical drugs (45.1%), unspecified substances (33.6%), alcohol and its surrogates (14.6%). Intoxications with alcohol and smoking mixtures were recorded in adolescents, mostly in boys. Among intoxications with drugs, poisonings with unspecified drugs dominated (33.6%), and among specified medicinal products – nasal decongestants (17.8%), sedatives and soporifics (13.3%), psychotropic (6.4%), hypotensive (6.8%), non-steroidal anti-inflammatory drugs (NSAIDs) (6.8%). In the department of pediatric resuscitation and intensive care, 230 children were treated. Among them: intoxications in result of an accident accounted for 60.3%, suicidal attempts – 4.3%, overdose of narcotic and psychotropic drugs in adolescents who have been using these drugs for a long time – 5.5%. Conclusions. In the structure of acute exogenous intoxications in children of the Ryazan region in 2013-2017 the most common were intoxications with drugs, unspecified substances, alcohol and its surrogates. Most often intoxications occurred in young children and adolescents, with a decrease in the proportion of young children and an increase in that of adolescents in dynamics. The proportion of alcohol intoxications, mainly in adolescents, increased 2.5 times during the observation period.