Potential Anti-inflammatory Effects of Lantana camara L.: A Review

Inflammatory diseases affect a large portion of the worldwide population, and chronic inflammation is a major risk factor for several dangerous pathologies. Increasing incidence and impact of inflammatory diseases have encouraged the search for new pharmacological strategies to face them. Lantana camara L. has been traditionally used as anti-inflammatory diseases, antipyretic, anti-ulcer, and wound healing property. Therefore, we aimed to obtain a comprehensive review regarding the anti-inflammatory activity of Lantana camara L. This review provides the evidence in the literature of the in vitro and in vivo anti-inflammatory activity of Lantana camara L. from 2010 to July 2020 without language restriction. Three bibliographical databases were used as information sources (PubMed, ScienceDirect, and Google Scholar). the search terms were “Anti-inflammatory” OR “Antiinflammatory” OR “Inflammation” AND “Lantana camara”. A total of 8 studies were included in this paper based on our eligibility criteria with 2 in vitro studies, 5 in vivo studies, and 1 study, a combination of in vivo and in vitro performed to substantiate the anti-inflammatory. This review has demonstrated the importance of Lantana camara L. as the potential for the natural anti-inflammatory. The set of pharmacological studies reported evidence of the Lantana camara L potential for the treatment of diseases associated with an inflammatory response. Studies have also affirmed the in vitro and in vivo anti-inflammatory properties of Lantana camara L., with several molecular mechanisms. Lantana camara L. has been reported to be able to inhibit Cox-2, LOX, NO, ROS, NF-kB, and reduce edema