A COMPREHENSIVE KINETIC STUDY OF THE EFFECT OF AQUO-PRIMARY ALCOHOL SOLVENT - SYSTEMS ON THE MEDICINAL EFFICIENCY OF CAPROATE ESTER

The medicinal efficiencies of propyl Caproate as a pharmaceutical were quantitatively determined by evaluating the changes in extensive thermodynamic properties of its solvolysis reaction in aquo-n-propanol media. It was observed that the values of iso- composition activation energy (EC) go on increasing with gradual addition of the organic cosolvent, but the values of iso-dielectric activation energy (ED) of the reaction was found decreasing with increasing dielectric constants of the reaction media. From the evaluated value of iso kinetic temperature (327) of the reaction, it is concluded that in this reaction media (water-n-propanol), there is appreciably strong solvent-solute interaction.