Repair CNS Injury by Combination of Olfactory Ensheathing Cells with Biomaterials | biomedgrid llc

Despite advances in understanding the failure of CNS to regenerate and technological improvements in post-injury rehabilitation, there is still no effective treatment for devastating injuries to the spinal cord. Cell transplantation has demonstrated to be one of the most promising therapeutic strategies to restore neurological functions after spinal cord injury (SCI). Olfactory ensheathing cells (OECs) are amongst the leading candidates in the field. OECs are specialized glial cells that can be obtained from either olfactory bulb or olfactory mucosa tissue. OECs are effective in anatomical repair and functional restoration in experimental injury models and in clinical application