Biomarker Studies for Early Detection of Chronic Kidney Disease (CKD)
Journal: IMPACT : International Journal of Research in Engineering & Technology ( IMPACT : IJRET ) (Vol.8, No. 10)Publication Date: 2020-10-31
Authors : Parvathareddy Sudha Malini S. Swathi; Ethakota Jahnavi;
Page : 7-18
Keywords : Chronic Kidney Disease; Serum Creatinine; Kidney Injury Molecule; SDS-PAGE; Quantitative Real Time PCR;
Abstract
Chronic Kidney Disease (CKD) represents a major challenge to public healthcare. Traditional clinical biomarkers of renal function (blood urea nitrogen and serum creatinine) are not sensitive or specific enough and only increase significantly after the presence of substantial CKD. Therefore, more sensitive biomarkers of CKD are needed. CKDspecific biomarkers at an early disease stage and early diagnosis of specific renal diseases would enable improved therapeutic treatment and reduce the personal and financial burdens.
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