The Gut Feeling of the Heat: Pathophysiological Pathways in the Gut-heart Axis in Celiac Disease
Journal: International Journal of Celiac Disease (Vol.8, No. 4)Publication Date: 2020-12-30
Authors : Aaron Lerner; Jozélio Freire de Carvalho;
Page : 120-123
Keywords : celiac disease; cardiovascular disease; microbiome; dysbiome; metabolome; nutrition; gut-heart axis; leaky gut; nutritional deficiency;
Abstract
The chain of events, starting from nutrients that change microbiome/dysbiome ratio followed by their secreted mobilome and ending with the leaky gut syndrome, can be applied for cardiovascular diseases. The Gut-heart axis is only one avenue where intestinal luminal eco-events induce remote organ's pathology. The present editorial highlights the mechanisms and potential pathways in the nutrients-microbiota-endocrine-cardiovascular axis that might affect human heart morbidity and mortality in celiac disease.
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