Ninhydrin as a novel and efficient catalyst for the synthesis of 2-amino-4H-Pyran derivatives in aqueous media usingJournal: Journal of Applied Organometallic Chemistry (Vol.1, No. 1)
Publication Date: 2021-02-01
Authors : Bita Baghernejad; Mahsa Fiuzat;
Page : 17-21
Keywords : 2-amino-4H-pyran; multi– component reaction; One-pot; ninhydrin;
< p>Benzopyranes and their derivatives are of interest due to their wide range of biological and medicinal properties. In this study, 2-amino-4H-pyran derivatives were obtained through a one-step multi-component reaction of aromatic aldehyde, malononitrile and dimedone in the presence of ninhydrin as a catalyst in water with high efficiency and short time.
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