Age aspect of adaptive response of the central nervous system in the state of emotional pain

The formation of higher adaptive response in the postoperative period was investigated in expe¬riments on rats of two age groups. It was found inhibition of the orientation-motor and emotional activity in young (5-6 months) and old rats (20-24 months) with the greatear effect in animals of the first age group. In young rats the inhibition of spatial memory was observed ? number of food-getting depleted reactions decreased by 28%. Cognitive deficit was accompanied by opposite changes in the content of free unsaturated fatty acids (C18: 2.3), respectively to age features: decreased by 46% in the cortex of young rats and increased by 2.5-fold in the hippocampus of old animals.