Study of eGFR in Type-2 Diabetes Mellitus

IntroductionDiabetic nephropathy (DN) is one of the most serious microvascularcomplication of Type-2 Diabetes Mellitus (Type-2 DM) which significantly impacts morbidity, mortality and quality of life. Estimated GFR is potentially an excellent method of detecting and monitoring renal failure. ObjectivesTo estimate and evaluate the correlation of fasting blood glucose, blood urea, serum creatinine& eGFR as biomarkers in detection of renal dysfunction in Type-2 diabetics as compared to healthy controls. MethodologyIn this study, 50 proven cases of Type-2 Diabetic patients and an equal number of age and sex matched healthy controls were included. Results The serum concentrations of FBG, Urea and Creatininewere increased and eGFR was decreased in Type-2 diabetic patients and were statistically highly significant (p,