Comparative Study to Evaluate Effect of IV Dexmedetomidine in Attenuating Hemodynamic&Recovery Responses During Extubation in General Anaesthesia

The prospective randomized comparative study was done to evaluate the effect of iv dexmedetomidine over hemodynamic and airway reflexes during extubation following various Surgeries under General Anaesthesia, study is randomized case control clinical trial with double blind method carried out in Ramkrishna CARE hospital Raipur (CG) during nov.2014-nov.2015, All the patients were observed for Hemodynamic responses � HR, SBP DBP, respiratory parameters i. e. RR and SpO2 and Airway reflexes � coughing, breath-holding, laryngospasm and bronchospasm at extubation. The increase in mean heart rate, blood pressure as a result of reflex symathoadrenal stimulation due to laryngoscopy and extubation is much higher in control group in comparison to dexmedetomidine group, no episode of desaturation were observed in both the groups, no signifivant change in respiratory rate were observed between both the groups.