Bacterial Biofilms: A Confrontation to Medical Science

Biofilms is a consortia of microorganisms in which microorganism adhere to a substratum in an irreversible manner and are enclosed in self produced matrix of extracellular polymeric substance. Common example of biofilm are dental plaque, device associated infection. Mostly biofilms are infective in nature and can be a source of Nosocomial infection. According to a report published by national institute of Health about 65 % of all microbial infections and 80 % of all chronic infections are associated with biofilms. The structural anatomy of biofilms protects microbial cells from antimicrobial agents, UV rays. These biofilms act as a barrier, antibiotics cannot reach to these microbes hindering the killing of the microbes thus posing a serious threat to public health. Management of these bacterial biofilms requires an early detection method and development of novel and efficient control measures for treating patients improving patient care and timely management