Ocular Manifestations in Cat IV Eligible and XDR Pulmonary and Extra Pulmonary Tuberculosis Patients in Government DOT Plus Centre

Background The prevalence and the patterns of ocular tuberculosis (TB) are largely undocumented among Multidrug Resistant TB (MDR-TB) and Extensive drug resistance TB (XDR TB) patients. Method A prospective study was conducted at department of Ophthalmology, NCH Surat from January 2015 to November 2016. Patients with established diagnosis of MDR and XDR, both pulmonary and extrapulmonary TB were recruited from the TB DOTS programme. Complete ocular examination including best corrected visual acuity (BCVA), colour vision, anterior segment and dilated posterior segment examination was carried out on all patients before starting treatment. These patients were followed monthly for first 6 months and then at twelfth month of diagnosis. The diagnosis of presumed ocular tuberculosis was made when clinical signs of tuberculosis (TB) uveitis were found in the participants. Result Seven (3.57 %) out of total 187 patients included in study showed signs of presumed ocular tuberculosis. There was no age, sex predilection between those who had presumed ocular TB and those who had not. Anterior uveitis was found in 1 (0.53 %) patient, choroiditis in 1 (0.53 %) patient, multifocal choroiditis in 1 (0.53 %) patient, Eales disease in 1 (0.53 %) patient, serpiginous choroiditis in 1 (0.53 %) patient, choroidal tubercle in 2 (1.07 %) patients. Conclusions Presumed ocular tuberculosis should be considered in MDR and XDR, both pulmonary and extrapulmonary TB patients. Common ocular lesion found in the study was choroidal tubercle