Evaluation of Glomerular Filtration Rate using 99mTc-DTPA Renal Scintigraphy

The evaluation of glomerular filtration rate GFR by using renal Scintigraphy with enhancement of gamma camera system using 99mTc-DTPA (185MBq) has been carried out among 149 patients of multi renal diseases and 48 as a control group with age between 20-80 year. The collected data was the age versus GFR, weight versus GFR, height versus GFR and the normal GFR, in addition to the general distribution of the sample based on the gender. Regarding GFR, the study reveals that the predominant mean of GFR was 82.5 ml/min among the age group of 20-30 years old and the maximum GFR was 85.2 ml/min among the age group of 30-40 years old. The researchers also found that the relationship between the age and GFR is an inverse relationship demonstrated by the following equation (), The results also reveal that the maximum mean of GFR is 86 ml/min, which is found among the weight group of 90-100 Kg, while the minimum GFR which is 81.5 ml/min was among the weight group of 40-50 Kg, indicating that the GFR increases as the weight increase. And the normal GFR among the Sudanese people in the range of 84 85.9 ml/min, the study also shows that the common people encountered at hospitals complaining of renal problems were having the weight between 40-70 Kg. The analysis of the study also reveals that the height has a poor relationship with GFR that could be demonstrated in a form of the following equation. The ultimate goal of the study is that the normal GFR which has been determine by gamma camera method is 85.5+/-14.2 mlmin with an accuracy equal to 85.5 % showing some advantages such as simple achieved accuracy, less time consuming, low radiation hazards, simplicity and non-invasive method relative to Single Injection Two Plasma methods SITPM which determined by Jacobson in 1985 with an accuracy equal to 84.75+/-16.63 ml/min.