Creatine Kinase for Prognostication in Organophosphorus Poisoning
Journal: International Journal of Science and Research (IJSR) (Vol.3, No. 11)Publication Date: 2014-11-05
Authors : Dayanand Raddi; Anikethana G V;
Page : 1336-1338
Keywords : creatine kinase; organophosphorus poisoning; acute poisoning; severity of poisoning; modified Dreisbach criteria;
Abstract
Organophosphorus poisoning is the responsible for a significant morbidity and mortality in agrarian countries. The incidence of poisoning is higher in young, economically active group with a case fatality rate of 10-20 %. Our study was done to evaluate the prognostic significance of Creatine kinase in organophosphorus poisoning. During the study period a total of 360 poisoning cases were admitted to the hospital of which 80 were eligible for the study. The mortality in patient with elevated creatine kinase was 39.47 % as against 4.76 % in patients with normal creatine kinase. It was statistically significant. Ventilator requirement in patients with elevated creatine kinase was statistically significant (44.74 % vs 9.52 %). The study emphasizes the role of creatine kinase in prognostication of patients presenting with organophosphorus poisoning.
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